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The Lab Notebook
Posts about
Tetramer
Tetramer
,
Immunology
,
Flow Cytometry
,
Immune Response
,
MHC
Correlation Between HLA Typing and Immune Monitoring in Human Disease
The HLA (human leukocyte antigen) system, also known as the human MHC (major histocompatibility...
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Tetramer
,
QuickSwitch
,
SARS-CoV-2
Human MHC Class II QuickSwitch™ Platform is used to Identify SARS-CoV-2 Virus Derived Peptides
In our previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) we have...
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Tetramer
,
QuickSwitch
,
SARS-CoV-2
How to Identify SARS-CoV-2 Virus Derived Peptides
In our previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) we have...
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Tetramer
,
QuickSwitch
,
SARS-CoV-2
Find Human MHC Class I Dominant Peptides
In our previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) we have...
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Tetramer
,
QuickSwitch
,
SARS-CoV-2
Comparing Theoretical Peptide-MHC Binding Affinity to Real Values produced by the QuickSwitch™ Platform
In our previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) we have
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Tetramer
,
QuickSwitch
,
covid-19
,
SARS-CoV-2
How to screen SARS-CoV-2 peptides to facilitate T cell research
Whenever our immune system is faced with a challenge, be it a multicellular parasite, a bacteria, a...
Read More
Tetramer
MuLV gp70 (AH1) Tetramer - a great tool for observing antigen specific immune response in cancer
MuLV gp 70, also designated as AH1 (SPSYVYHQF), is an endogenous viral envelope glycoprotein...
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Tetramer
,
QuickSwitch
In vivo NIRF whole-body imaging through MHC tetramers
The use of MHC tetramers for the detection of antigen specific T cells has been a well-established...
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Tetramer
,
Peptide
,
covid-19
,
SARS-CoV-2
,
vaccine
,
MHC
Screening for COVID-19 T-cell peptides and immune monitoring with MHC tetramers in a single assay
COVID-19 infected cells can be recognized by T-cells only after SARS-CoV-2 peptides are processed...
Read More
Tetramer
,
Cancer
Cancer Immunotherapy - Growing focus on CD4+ T lymphocytes and MHC Class II Neoantigens
It is now well accepted that CD8+ T cells play a central role in mediating anti-tumor immunity by...
Read More
Tetramer
,
Cancer
,
t cell
Is your drug candidate able to reverse the T Cell Exhaustion-like state in our in vitro functional screening assay?
The goal of cancer immune checkpoint therapies is to cure tumor-specific T cells from dysfunction...
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Tetramer
,
Immunology
,
tuberculosis
New tetramer for vaccine research targeting Tuberculosis and Ag85B specific T-cells
Tuberculosis (TB) is caused by the Mycobacterium tuberculosis and usually targets the lungs. This...
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Tetramer
,
QuickSwitch
QuickSwitch, a tool for adoptive T cell transfer
Our understanding of how the immune system responds to cancer has increased by leaps and bounds in...
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Tetramer
,
Flow Cytometry
Gating strategy for tetramer analysis to eliminate non-specific event
While MHC tetramer staining of antigen specific T cells for flow cytometry is considered highly...
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Tetramer
Which tetramers can be used for my mouse samples?
The thymus shapes a host's T-cell repertoire so they do not respond to "self" antigens, yet are...
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Tetramer
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QuickSwitch
,
Peptide
,
Peptide Exchange
Quick! Switch out your peptide!
The immunotherapy field is making great progress in aiding many disease treatments. The hope is...
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Tetramer
,
QuickSwitch
,
Peptide
,
Peptide Exchange
Quick! Switch out your peptide!
The immunotherapy field is making great progress in aiding many disease treatments. The hope is...
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Tetramer
Don't be fooled. Not all tetramers are created equal!
Have you seen comparisons of multimer technology claiming to be superior to tetramers? Be sure to...
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Tetramer
Help! My mouse tetramer stained ALL the CD8+ T cells!
You’re sitting at your flow cytometer, staring at your CD8 x tetramer plot in anticipation of a...
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Tetramer
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Immunology
Be positive! 5 ways to confirm your MHC tetramer is binding
In the previous Tetramer Tips blog, I suggested ways for you to be a negative Control Freak. Now...
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Tetramer
,
Immunology
Tetramer Tips for Success: How to be a (Negative) Control Freak
While being a Control Freak may not be the best choice for living in spiritual harmony, it is a...
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