--- title: Stabilizing cellular antigens the easy way using Transfix description: Do you have trouble preserving precious blood samples? Find out how Transfix will help with cell stabilization. image: https://blog.mblintl.com/hubfs/transfix.png --- **Please Note:** MBL International will be shutting down its operations effective December 31, 2024. Distribution of MBL products in the United States will be transferred to Cosmo Bio US on January 1st while European Distributors will remain unchanged. For any US inquiries regarding orders or support during this transition, reach out to Cosmo Bio: [https://www.cosmobiousa.com/](https://www.cosmobiousa.com/). For Non-US inquiries reach out to MBL in Japan: [https://www.mblbio.com/](https://www.mblbio.com/). 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[Home](https://blog.mblintl.com/) - [Blogs](https://blog.mblintl.com) - Stabilizing cellular antigens the easy way using Transfix # Stabilizing cellular antigens the easy way using Transfix ### Topics - Select Topic - 3D Cell Culture Advancements in Metabolism Research Allergy Antibodies Antibody Antibody Reagents Antibody-Peptide Conjugates Apoptosis Assay and Kits Autoimmune Disease Autophagy BRIC Benefits of Tetramer Assays Biomarker Cancer Cell Biology Cell Culture Reagents Cell Stabilization Custom Peptide Synthesis Cytokine Dextramer Staining Drug Discovery ELISA Epigenetics Epitope Tag Exosome Exosomes FCM Fc blocker Flow Cytometry Flow Cytometry Antibodies Fluoppi Fluorescent Proteins Future of Tetramer Technology Gastric Inhibitory Peptide Gene Regulation Gene Therapy Green Fluorescent Protein IL-18 Immune Response Immunology Inflammation Isotype Control Kits and Assays LC3 Liquid Biopsy MHC MHC Alleles MHC Class II Tetramers MHC Peptides Contribute MHC Tetramer MHC Tetramer Protocol MHC tetramer advancements Metabolism Mitophagy NCP Neuroscience Neuroscience Reagents Organoid PCSK9 PCSK9 ELISA Kit Peptide Peptide Exchange Peptide Synthesis Methods Peptide Synthesis Service Peptide-Infused Skin Care Products Preservation Purify exosome Quality Control QuickSwitch Quickswitch™ Custom Tetramer Kits RBP RIP Chip RNA Recombinant Protein Production Recombinant Proteins Regulation RiboTrap S100 Proteins SARS-CoV-2 T-Cell Detection TCR Tetramers Tetramer Tetramer Analysis Tetramer Assay Tetramer Assay Protocol Tetramer Staining TransFix Vectors Western Reagents atg8 covid-19 gfp keima red kinases mitochondria cell death p62 pathways phosphorylation pro IL-18 reagents rfp t cell tuberculosis ultracentrifugation vaccine ### Top Posts ### Subscribe to our Blogs Published by [Anthony G Pietrantoni](https://blog.mblintl.com/author/anthony-g-pietrantoni) on Mar 29, 2019 1:00:00 PM ![](https://blog.mblintl.com/hubfs/transfix.png) Many researchers and clinicians have issues with keeping their whole blood or CSF samples viable over time. Whether the reason is because the collection occurred on a Friday afternoon with no lab analysis available until Monday, or collecting a large batch of samples to send out to the lab at the other end or the state, cellular degradation can be a problem. Don’t let this happen to you. Without stabilization, flow cytometric analysis of blood samples must be performed within 48 hours of venepuncture, as apoptosis and proteolytic degradation of cellular markers will detrimentally affect the immunophenotypic profile. Blood samples older than 48 hours are often no longer suitable for flow cytometric examination, exhibiting indistinguishable cell subsets and inaccurate absolute cell counts leading to erroneous clinical results. This may require a fresh sample to be taken, incurring extra costs and delayed analysis.   Various assays that are used for analyzing the immunophenotypic profile of whole blood or cerebrospinal fluid (CSF), are compromised because the cell surface antigens start degrading immediately upon venipuncture or lumbar puncture, particularly leukocytes within CSF samples. An unwanted result can be painful and costly for repeat drawings. If you have ever had to perform a repeat draw on a child, you know how unpleasant that can be for everyone involved.   TransFix is a patented general purpose reagent that is easy to use and preserves cells and cellular antigens. It has been used to stabilize antigens for up to 14 days prior to analysis, depending on the application.   **Key Benefits of TransFix:![TransFixnewimage](https://blog.mblintl.com/hs-fs/hubfs/TransFixnewimage.jpg?width=535&name=TransFixnewimage.jpg)** The components of TransFix stabilize cellular markers, allowing analysis by flow cytometry to be carried out at a more convenient time for the user. TransFix can be used in clinical diagnostic testing, clinical trials and a wide range of research applications.   Tags: [FCM](https://blog.mblintl.com/topic/fcm), [TransFix](https://blog.mblintl.com/topic/transfix), [Preservation](https://blog.mblintl.com/topic/preservation), [Cell Stabilization](https://blog.mblintl.com/topic/cell-stabilization) --- [Back to Blog](https://blog.mblintl.com) --- ### Comments Or Suggestions ## Related Articles ### Sign up for our latest news and promotions. 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