Ever wonder how cholesterol levels are regulated? One of the major regulators is a molecule called proprotein convertase subtilisin/kexin type 9 or PCSK9 for short! PCSK9 has been implicated in causing hypercholesterolemia (high cholesterol), and diseases such as coronary heart disease1.
This blog post will get you caught up on cholesterol and research on PCSK9's role in cholesterol regulation.
PCSK9 ELISA Kits and Antibodies
Measuring levels of PCSK9 is important for researchers who are trying to regulate cholesterol.
1. Farnier M. PCSK9: From discovery to therapeutic applications. Arch Cardiovasc Dis. 2014;107(1):58-66.
2. Nlm.nih.gov. Cholesterol Levels: What You Need to Know | NIH MedlinePlus the Magazine. 2015.
3. Ahn CH, Choi SH. New drugs for treating dyslipidemia: beyond statins. Diabetes Metab J. 2015;39(2):87-94.
4. Levy E, Ben djoudi ouadda A, Spahis S, et al. PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells. Atherosclerosis. 2013;227(2):297-306.
5. Seidah NG, Sadr MS, Chrétien M, Mbikay M. The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions. J Biol Chem. 2013;288(30):21473-81.