Cell-based assays are the first step for drug screening applications and have been performed in monolayer culture condition for decades. These traditional cell cultures have been known to enhance integrin signals, which mask several biologic activities in tumor cells. In contrast, it is already known that 3D cell culture can replicate the intra-tumor microenvironment.
3D cell culture innovation ensures that time spent at the bench will correlate to in vivo environments, with possibilities to aid in future discoveries such as drug delivery into tumor cells or understanding tissue microenvironment. Typically, a researcher use a conventional 2D cell culture technique but are limited to what observations they can truly make. NanoCulture Plate 3D platform has been designed to facilitate researchers’ time in the lab.